BOUNDED AND CATEGORIZED: TARGETING DATA ASSIMILATION FOR SEA ICE FRACTIONAL COVERAGE AND NONNEGATIVE QUANTITIES IN A SINGLE-COLUMN MULTI-CATEGORY SEA ICE MODEL

Bounded and categorized: targeting data assimilation for sea ice fractional coverage and nonnegative quantities in a single-column multi-category sea ice model

A rigorous exploration of the sea ice data assimilation (DA) problem using a framework specifically developed for rapid, interpretable hypothesis testing is presented.In many applications, DA is implemented to constrain a modeled estimate of a state with observations.The sea ice DA application is complicated by the wide range of spatiotemporal scal

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Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis

Immunoglobulin light chain (AL) amyloidosis is a rare plasma cell dyscrasia characterized by the deposition of abnormal amyloid fibrils in multiple organs, thus impairing their function.In the largest cohort studied up to now of 118 CD138-purified plasma cell samples from previously untreated immunoglobulin light chain amyloidosis patients, we asse

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